Cardiovascular physiology

MiR-21-5p Protects Embryonic Growth and Heart Function During Developmental Hypoxia by Dampening HIF Responses and Altering Gene Expression

Fetal hypoxia is a common complication of pregnancy that increases cardiovascular risk in offspring. This study tests whether miR-21-5p upregulation during developmental hypoxia protects embryonic growth and cardiac function. Using neonatal rat …