Long-read sequencing
Sequencing genomes, transcriptomes, and epigenomes at UOH
SeqUOH is centered on Oxford Nanopore sequencing for whole-genome sequencing, targeted sequencing, direct RNA applications, and methylation-aware analysis. The platform is integrated with Kütral HPC so projects can move directly from data generation into reproducible downstream workflows.
- Platforms
- GridION and P2 Solo
- Output
- 10 to 580 Gb per run
- Applications
- Assembly, SV, direct RNA, methylation
Use cases
What the platform supports
01
Cancer genomics and structural variation
Long reads help resolve complex rearrangements, copy-number structures, phased variants, and difficult tumor regions.
02
Genome assembly and haplotypes
High molecular continuity supports de novo assembly, reference construction, and haplotype-aware reconstruction.
03
Population and comparative genomics
The platform supports Chilean genomic diversity studies, comparative genomics, and evolutionary analyses.
04
Epigenomic applications
Nanopore data can preserve methylation-aware signals that are difficult to access with short-read assays alone.
For compute and workflow execution, see the Kütral HPC page.